A gastrointestinal cocktail, known as a GI cocktail, is a generic term for a mixture of liquid antacid, viscous lidocaine, and an anticholinergic primarily used to treat dyspepsia.[1] The GI cocktail may also deceptively mask pain originating from the heart.[2]
There is a wide variety of GI cocktail recipes in use today. A very popular one is a mixture of Maalox, Donnatal, and viscous lidocaine, in equal parts.[3] A mixture of 10 ml Mylanta, 10 ml Donnatal and 10 ml viscous lidocaine is known as "The Green Goddess".[4] The efficacy of this mixture for the treatment of dyspepsia is generally considered superior to treatment with only any one of its components, due to their varied mechanisms of relief; however, a recent study found that a GI cocktail was no more effective in relieving stomach pain than an antacid alone.[5]